The Heart House has the largest Cardiovascular Clinical Research Department in the region. This allows us access to the most modern drugs and equipment for patient care.

Current research trials include:

Dal-Outcomes — Roche: A phase III study to evaluate the effects of dalcetrapib on cardiovascular risk in stable CHD, with a recent Acute Coronary Syndrome
Principal Investigators: Sanford J. Gips (Haddon Heights); Dilip B. Viswanath (Sewell)

ASCEND — J & J Pharmaceuticals: Acute Study of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure.
Principal Investigators: Mark D. Gelernt (Elmer); Jeffrey H. Kramer (Sewell).

TIMI 50 – Tra2p — Schering Plough: Clinical Study to evaluate the safety and efficacy of SCH530348 in addition to Standard of Care in subjects with a history of Atherosclerotic Disease
Principal Investigator: Mark D. Gelernt (Elmer); Jeffrey H. Kramer (Sewell); Sanford J. Gips (Haddon Heights)

Aristotle — Bristol Meyers Squibb: A phase III active Warfarin controlled study to evaluate safety and efficacy of Apixaban in preventing stroke and systemic embolism in subjects with nonvalvular atrial fibrillation.
Principal Investigators: Harvey A. Snyder (Haddon Heights); Mark D. Gelernt (Elmer); Jeffrey H. Kramer (Sewell)

MK0653-139 — Merck & Co., Inc: Titration study to evaluate the safety and efficacy of Ezetimibe added onto Rosuvastatin vs. up titration of Rosuvastatin in patients with hypercholesterolemia at risk for coronary heart disease.
Principal Investigator: Jeffery H. Kramer (Sewell)

SOLID — GlaxoSmithKline: A clinical outcomes study of darapladib vs. placebo in subjects following acute coronary syndrome to compare incidence of major adverse cardiovascular events.
Principal Investigators: Mark D. Gelernt (Elmer); Jeffrey H. Kramer (Sewell); Harvey A. Snyder (Haddon Heights)

SCORE — Spirocor Ltd: A clinical study to validate the accuracy of the SPIROCOR respiratory stress test system in indicating the presence of significant coronary artery disease (S-CAD)
Principal Investigator: Georges I. Kaddissi (Cherry Hill); Jeffrey H. Kramer (Sewell); Mark D. Gelernt (Elmer)

ELEVATE — Sanofi Aventis: A clinical study to evaluate higher maintenance doses of clopidogrel can overcome the reduced pharmacologic response to the currently recommended dose of clopidogrel seen in carriers of a reduced function CYP2C19 allele.
Principal Investigator: Dilip B. Viswanath (Elmer); Jeffrey H. Kramer (Sewell); Sanford J. Gips (Haddon Heights)

MYNX M5 — CADV/Access Closure: Investigator driven clinical trial to assess the safety of ambulation after one hour after placement of the Mynx M5 closure device.
Principal Investigator: Vijayendra K. Verma (Our Lady of Lourdes Medical Center)

SEPIA 2 — Sanofi Aventis: A clinical study to compare the efficacy of otamixaban with unfranctionated heparin + eptifibatide in patients with unstable angina/non ST segment MI scheduled to undergo an early invasive strategy.
Principal Investigator: Vijayendra K. Verma (Our Lady of Lourdes Medical Center); Sanford J. Gips (Cooper University Hospital)

XIENCE V — Abbott Vascular: XIENCE V® Everolimus Eluting Coronary Stent System (EECSS) USA Post Approval Study.
Principal Investigator: Georges I. Kaddissi (Our Lady of Lourdes Medical Center); Sanford J. Gips (Sub-Investigator – Cooper University Hospital)

DAPT — Harvard Clinical Research Institute: To assess effectiveness and safety of 12 vs. 30 months dual antiplatelet therapy (DAPT) in subjects undergoing PCI with either drug-eluting stent or bare metal stent placement for the treatment of coronary artery lesions.
Principal Investigator: Georges I. Kaddissi (Our Lady of Lourdes Medical Center)

CHOICE — Abbott Vascular: Carotid stenting for high risk patients; evaluating outcomes through the collection of clinical evidence.
Principal Investigator: Ronald A. Cohen (Our Lady of Lourdes Medical Center)

ACT 1 — Abbott Vascular: Asymptomatic Carotid stenosis versus endarterectomy trial.
Principal Investigator: Ronald A. Cohen (Our Lady of Lourdes Medical Center)

SAPPHIRE — Cordis: Stenting and angioplasty with protection in patients at high risk for endarterectomy.
Principal Investigator: Ronald A. Cohen (Our Lady of Lourdes Medical Center); Sanford J. Gips, Georges I. Kaddissi, Kartik S. Giri, Vijayendra K. Verma, (Sub Investigators- Cooper University Hospital).

CHAMPION — The Medicines Company: A clinical trial comparing Cangrelor to clopidogrel in subjects who require percutaneous coronary intervention.
Principal Investigator: Sanford J. Gips (Cooper University Hospital); Vijayendra K. Verma (Our Lady of Lourdes Medical Center)

PLATINUM — Boston Scientific Corporation: Assess an Everolimus-Eluting Coronary Stent system (PROMUS Element™) for the treatment of up to two de novo coronary artery lesions.
Principal Investigator: Sanford J. Gips (Cooper University Hospital)

ROCKET — Johnson & Johnson: A study comparing the efficacy and safety of Once-Daily Oral Rivaroxaban with adjusted-dose oral Warfarin for the prevention of stroke in patients with atrial fibrillation.
Principal Investigator: Harvey A. Snyder (Haddon Heights); Mark D. Gelernt (Elmer)

CYPRESS — Cordis: Assess the effectiveness and safety of different durations of dual anti-platelet therapy (DAPT) in subjects undergoing percutaneous coronary intervention with the CYPHER® Sirolimus-eluting coronary stent.
Sub-Investigators: Sanford J. Gips, Georges I. Kaddissi, Andrew P. Zinn, Philip A. Koren (Cooper University Hospital); Kartik S. Giri, Vijayendra K. Verma, Ronald A. Cohen (our Lady of Lourdes Medical Center)

 

The Heart House is affiliated with the following hospitals:

Cooper University Hospital
Camden, New Jersey

Kennedy Memorial Hospital - Cherry Hill
Cherry Hill, New Jersey

Kennedy Memorial Hospital - Washington Township
Washington Township, New Jersey

Our Lady of Lourdes Medical Center
Camden, New Jersey

South Jersey Hospital Systems - Elmer
Elmer, New Jersey

South Jersey Regional Medical Center - Vineland
Vineland, New Jersey

Virtua West Jersey Hospital - Berlin
Berlin, New Jersey

Virtua West Jersey Hospital - Marlton
Marlton, New Jersey

Virtua West Jersey Hospital - Voorhees
Voorhees, New Jersey