CADV has the largest Cardiovascular Clinical Research Department in the region. This allows us access to the most modern drugs and equipment for patient care.
CADV's current research trials include:

ACCOMPLISH — Avoiding Cardiovascular Events through COMbination Therapy in Patients Living with Systolic Hypertension A prospective, multinational, multicenter, double-blind, randomized,active-controlled trial to compare the effects of Lotrel (amlodipine/benazepril) to Benazepril and Hydrochlorthiazide combined on the reduction of cardiovascular morbidity and mortality in patients with high risk hypertension
Sponsor: Novartis
Principle Investigators: Mark D. Gelernt (Elmer), Jeffrey H. Kramer(Haddon Heights)

ACT — Advancements in ICD Therapy (ACT) Registry
Sponsor: St. Jude Medical

ACT I — (Pending)

ACTIVE — Atrial Fibrillation Clopidogrel Trial with Irbesartan for the prevention of Vascular Events
A parallel randomized controlled evaluation of Clopidogrel plus aspirin, with factorial evaluation of irbesartan, for the prevention of vascular events, in patientys with atrial fibrillation
Sponsor: Sanofi-Synthelabo Research
Principle Investigator: Mark D. Gelernt

ARRIVE 2 — Taxus Stent Safety Registry
Sponsor: Boston Scientific

ASPEN — To determine if AF suppression pacing will prevent first episode of atrial fibrillation in high risk patients.
Sponsor: St. Jude
Principle Investigator: Steven A. Levi

CAPTURE 2 — Stent Registry Carotid Disease High Risk Surgical patients
Sponsor: Guidant
Principle Investigator: Ronald A. Cohen (Our Lady of Lourdes)

CETP — Torceptrapib/Atorvastatin vs. Atorvastatin alone for subjects with coronary heart disease or risk equivalent
Note: Study Terminated by sponsor
Sponsor: Pfizer
Principle Investigators: Mark D. Gelernt (Elmer), Jeffrey H. Kramer (Haddon Heights)

CHAMPION PCI — A clinical trial comparing Cangrelor to Clopidogrel in subjects requiring PCI
Sponsor:The Medicines Company
Principle Investigators: Jeffrey H. Kramer (Our Lady of Lourdes), Sanford J. Gips (Cooper)

CHOICE — Carotid stenting for High Surgical Risk Patients; Evaluating Outcomes Through the Collection of Clinical Evidence
Sponsor: Abbott Vascular
Principle Investigator: Ronald A. Cohen (Our Lady of Lourdes)

EXACT — Emboshield and Xact Post Approval Carotid Stent trial using the Emboshield Barewire Rapid Exchange Carotid Stent System
Sponsor: Abbott Vascular
Principle Investigator: Ronald A. Cohen (Our Lady of Lourdes)

EZ PATH — Ezetimibe Plus Atorvastatin titration in achieving lower LDL-C Targets in Hypercholesterolemic patients A Multicenter, Randomized, Double-blind, Titration Study to Evaluate and Compare the Efficacy and Safety of Ezitimibe Added on to Atorvastatin 40 mg versus up Titration to Atorvastatin 80 mg in Hypercholesterolemic Patients at High Risk for Coronary Heart Disease Not Adequately controlled on Atorvastatin 40 mg or its equivalent. (10-12 week study)
Sponsor: Merck
Principle Investigator: Mark D. Gelernt (Elmer)

FOCUS — Follow up Of Clinical Outcomes: The Long-term AGI-1067 plus Usual Care Study (ARISE extension)
Sponsor: AtheroGenics, Inc.
Principle Investigator: Mark D. Gelernt (Elmer), Michael B. Herlich (Haddon Heights)

IMPROVE-IT — A Multicenter, Double- Blind, Randomized Study to Establish the Clinical Benefit and Safety of Vytorin (Ezetimibe/Simvastatin Tablrt) vs Simvastatin Monotherapy in High-Risk Subjects Presenting with Acute Coronary Syndrome
Sponsor: Schering-Plough Research Institute
Principle Investigator: Jeffrey H. Kramer (Our Lady of Lourdes), Sanford J. Gips (Cooper)

I-PRESERVE — Irbesartan in Heart failure with Preserved Systolic Function
Sponsor: Bristol-Myers Squibb Pharmaceutical Research Institute
Principle Investigator: Mark D. Gelernt (Elmer)

Midlife Device Memory Data Collection
Sponsor: Boston Scientific
Principle Investigator: Steven D. DaTorre

PAS — Evaluation of long term performance of CRT-D or biventricular pacing systems and left heart leads.
Sponsor: St. Jude
Principle Investigator: Steven D. DaTorre

Rapid RF Registry — Remote Active Monitoring in Patients with Heart Failure
Sponsor: Guidant
Principle Investigator: Steven A. Levi

RATE — Registry of AT/AF Episodes in the CRM Device Population
Sponsor: St. Jude
Principle Investigator: Steven D. DaTorre

RE-LY — Study of stroke prevention in atrial fibrillation Randomized Evaluation of Long term anticoagulant therapy (RE-LY) comparing the efficacy and safety of two blinded doses of dabigatran etexilate with open label warfarin for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: prospective, multicentre, parallel-group, non-inferiority trial
Sponsor: Boehringer Ingelheim
Principle Investigators: Mark D. Gelernt (Elmer) Jeffrey H. Kramer (Haddon Heights)

Respone HF A — study evaluate the benefit of V-V Timing in reducing the non-responder rate in CRT-D patients.
Sponsor: Guidant
Principle Investigator: Steven A. Levi

TRENDS — To determine of Atrial Tachycardia/Atrial Fibriliation burden over 30 days is an independent predictor of occurrences of ischemic stroke, TIA, or non-stroke systemic embolism in subjects not receiving anticoagulation therapy
Sponsor: Medtronic
Principle Investigator: Steven D. DaTorre

TRITON TIMI 38 — A comparison of CS-747 and Clopidogrel in Acute Coronary Subjects who are to Undergo Percutaneous Coronary Intervention. A Phase 3, randomized, parallel-group, double-blind, double-dummy, active-controlled study.
Sponsor: Eli Lily and Company
Principle Investigator: Sanford J. Gips (Cooper)

 

CADV is affiliated with the following hospitals:

Cooper University Hospital
Camden, New Jersey

Kennedy Memorial Hospital - Cherry Hill
Cherry Hill, New Jersey

Kennedy Memorial Hospital - Washington Township
Washington Township, New Jersey

Our Lady of Lourdes Medical Center
Camden, New Jersey

South Jersey Hospital Systems - Elmer
Elmer, New Jersey

South Jersey Regional Medical Center - Vineland
Vineland, New Jersey

Virtua West Jersey Hospital - Berlin
Berlin, New Jersey

Virtua West Jersey Hospital - Marlton
Marlton, New Jersey

Virtua West Jersey Hospital - Voorhees
Voorhees, New Jersey