CADV has the largest Cardiovascular Clinical Research Department in the region. This allows us access to the most modern drugs and equipment for patient care.
CADV's current research trials include:

Dal-Outcomes — Roche: A phase III study to evaluate the effects of dalcetrapib on cardiovascular risk in stable CHD, with a recent Acute Coronary Syndrome
Principal Investigators: Sanford J. Gips (Haddon Heights); Dilip B. Viswanath (Sewell)

ASCEND — J & J Pharmaceuticals: Acute Study of Clinical Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure.
Principal Investigators: Mark D. Gelernt (Elmer); Jeffrey H. Kramer (Sewell).

TIMI 50 – Tra2p — Schering Plough: Clinical Study to evaluate the safety and efficacy of SCH530348 in addition to Standard of Care in subjects with a history of Atherosclerotic Disease
Principal Investigator: Mark D. Gelernt (Elmer); Jeffrey H. Kramer (Sewell); Sanford J. Gips (Haddon Heights)

Aristotle — Bristol Meyers Squibb: A phase III active Warfarin controlled study to evaluate safety and efficacy of Apixaban in preventing stroke and systemic embolism in subjects with nonvalvular atrial fibrillation.
Principal Investigators: Harvey A. Snyder (Haddon Heights); Mark D. Gelernt (Elmer); Jeffrey H. Kramer (Sewell)

MK0653-139 — Merck & Co., Inc: Titration study to evaluate the safety and efficacy of Ezetimibe added onto Rosuvastatin vs. up titration of Rosuvastatin in patients with hypercholesterolemia at risk for coronary heart disease.
Principal Investigator: Jeffery H. Kramer (Sewell)

SOLID — GlaxoSmithKline: A clinical outcomes study of darapladib vs. placebo in subjects following acute coronary syndrome to compare incidence of major adverse cardiovascular events.
Principal Investigators: Mark D. Gelernt (Elmer); Jeffrey H. Kramer (Sewell); Harvey A. Snyder (Haddon Heights)

SCORE — Spirocor Ltd: A clinical study to validate the accuracy of the SPIROCOR respiratory stress test system in indicating the presence of significant coronary artery disease (S-CAD)
Principal Investigator: Georges I. Kaddissi (Cherry Hill); Jeffrey H. Kramer (Sewell); Mark D. Gelernt (Elmer)

ELEVATE — Sanofi Aventis: A clinical study to evaluate higher maintenance doses of clopidogrel can overcome the reduced pharmacologic response to the currently recommended dose of clopidogrel seen in carriers of a reduced function CYP2C19 allele.
Principal Investigator: Dilip B. Viswanath (Elmer); Jeffrey H. Kramer (Sewell); Sanford J. Gips (Haddon Heights)

MYNX M5 — CADV/Access Closure: Investigator driven clinical trial to assess the safety of ambulation after one hour after placement of the Mynx M5 closure device.
Principal Investigator: Vijayendra K. Verma (Our Lady of Lourdes Medical Center)

SEPIA 2 — Sanofi Aventis: A clinical study to compare the efficacy of otamixaban with unfranctionated heparin + eptifibatide in patients with unstable angina/non ST segment MI scheduled to undergo an early invasive strategy.
Principal Investigator: Vijayendra K. Verma (Our Lady of Lourdes Medical Center); Sanford J. Gips (Cooper University Hospital)

XIENCE V — Abbott Vascular: XIENCE V® Everolimus Eluting Coronary Stent System (EECSS) USA Post Approval Study.
Principal Investigator: Georges I. Kaddissi (Our Lady of Lourdes Medical Center); Sanford J. Gips (Sub-Investigator – Cooper University Hospital)

DAPT — Harvard Clinical Research Institute: To assess effectiveness and safety of 12 vs. 30 months dual antiplatelet therapy (DAPT) in subjects undergoing PCI with either drug-eluting stent or bare metal stent placement for the treatment of coronary artery lesions.
Principal Investigator: Georges I. Kaddissi (Our Lady of Lourdes Medical Center)

CHOICE — Abbott Vascular: Carotid stenting for high risk patients; evaluating outcomes through the collection of clinical evidence.
Principal Investigator: Ronald A. Cohen (Our Lady of Lourdes Medical Center)

ACT 1 — Abbott Vascular: Asymptomatic Carotid stenosis versus endarterectomy trial.
Principal Investigator: Ronald A. Cohen (Our Lady of Lourdes Medical Center)

SAPPHIRE — Cordis: Stenting and angioplasty with protection in patients at high risk for endarterectomy.
Principal Investigator: Ronald A. Cohen (Our Lady of Lourdes Medical Center); Sanford J. Gips, Georges I. Kaddissi, Kartik S. Giri, Vijayendra K. Verma, (Sub Investigators- Cooper University Hospital).

CHAMPION — The Medicines Company: A clinical trial comparing Cangrelor to clopidogrel in subjects who require percutaneous coronary intervention.
Principal Investigator: Sanford J. Gips (Cooper University Hospital); Vijayendra K. Verma (Our Lady of Lourdes Medical Center)

PLATINUM — Boston Scientific Corporation: Assess an Everolimus-Eluting Coronary Stent system (PROMUS Element™) for the treatment of up to two de novo coronary artery lesions.
Principal Investigator: Sanford J. Gips (Cooper University Hospital)

ROCKET — Johnson & Johnson: A study comparing the efficacy and safety of Once-Daily Oral Rivaroxaban with adjusted-dose oral Warfarin for the prevention of stroke in patients with atrial fibrillation.
Principal Investigator: Harvey A. Snyder (Haddon Heights); Mark D. Gelernt (Elmer)

CYPRESS — Cordis: Assess the effectiveness and safety of different durations of dual anti-platelet therapy (DAPT) in subjects undergoing percutaneous coronary intervention with the CYPHER® Sirolimus-eluting coronary stent.
Sub-Investigators: Sanford J. Gips, Georges I. Kaddissi, Andrew P. Zinn, Philip A. Koren (Cooper University Hospital); Kartik S. Giri, Vijayendra K. Verma, Ronald A. Cohen (our Lady of Lourdes Medical Center)

 

CADV is affiliated with the following hospitals:

Cooper University Hospital
Camden, New Jersey

Kennedy Memorial Hospital - Cherry Hill
Cherry Hill, New Jersey

Kennedy Memorial Hospital - Washington Township
Washington Township, New Jersey

Our Lady of Lourdes Medical Center
Camden, New Jersey

South Jersey Hospital Systems - Elmer
Elmer, New Jersey

South Jersey Regional Medical Center - Vineland
Vineland, New Jersey

Virtua West Jersey Hospital - Berlin
Berlin, New Jersey

Virtua West Jersey Hospital - Marlton
Marlton, New Jersey

Virtua West Jersey Hospital - Voorhees
Voorhees, New Jersey